Effects of antiepileptic drugs on serum lipids profile among young adult Sudanese patient with epilepsy at Aljazeera State

consequences that lead to an increase in risk of atherosclerosis patients with epilepsy, several studies have reported the commonly used antiepileptic drugs like phenytoin, and carbamazepine serum total Cholesterol, High Density Lipoproteins Cholesterol (HDL-C) Low lipoprotein ( LDL-C ) levels Triglyceride (TG) .The aim this study assess compare lipid profile young adult treated by anti-epileptic (phenytoin, oxcarbazepine valproic acid) . Materials Methods a cross-sectional was conducted Aljazeera state. Epileptic were recruited. taking for more than six months on regular follow up; approximately 120 (40 40 oxcarbazepine, Acid). Age sex matching controls taken. our results show significant difference mean TC, TG, HDL, group receiving phenytoin when compared control P value (0.00) all profile. Also between HDL-C (0.00 From present we concluded CYP enzyme inducer medicines is strongly associated increased LDL-C, where asvalproate showed no change. Therefore, cholesterol level should be regularly monitored undergoing. Therapy medicines.